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Abdominal fat distribution

Abdominal fat distribution

Booth, A. In Dat Biobank disease outcomes analyses, prevalent Abdominal fat distribution status was defined dietribution Abdominal fat distribution binary variable and logistic regression was used to estimate the odds ratio OR of disease per 1-SD increase in BMI-adjusted WHR due to a given polygenic score. Votruba, S. Suzuki R, Watanabe S, Hirai Y, et al.

Abdominal fat distribution -

Led by Naiman Khan , an Illinois professor of kinesiology and community health , the researchers published their study, funded by the Hass Avocado Board, in the Journal of Nutrition. Edit embedded media in the Files Tab and re-insert as needed. Individuals with a higher proportion of that deeper visceral fat tend to be at a higher risk of developing diabetes.

The participants were divided into two groups. One group received meals that incorporated a fresh avocado, while the other group received a meal that had nearly identical ingredients and similar calories but did not contain avocado.

Female participants who consumed an avocado a day as part of their meal had a reduction in visceral abdominal fat — the hard-to-target fat associated with higher risk — and experienced a reduction in the ratio of visceral fat to subcutaneous fat, indicating a redistribution of fat away from the organs.

However, fat distribution in males did not change, and neither males nor females had improvements in glucose tolerance. Learning that the benefits were only evident in females tells us a little bit about the potential for sex playing a role in dietary intervention responses.

The degree of masculine differentiation of obesities: a factor determining predisposition to diabetes, atherosclerosis, gout, and uric calculous disease. Am J Clin Nutr. doi: Obesity and the risk of myocardial infarction in 27, participants from 52 countries: a case-control study.

Biggs ML, Mukamal KJ, Luchsinger JA, et al. Association between adiposity in midlife and older age and risk of diabetes in older adults. Langenberg C, Sharp SJ, Schulze MB, et al; InterAct Consortium. Long-term risk of incident type 2 diabetes and measures of overall and regional obesity: the EPIC-InterAct case-cohort study.

PLoS Med. Stefan N, Häring HU, Hu FB, Schulze MB. Metabolically healthy obesity: epidemiology, mechanisms, and clinical implications. Lancet Diabetes Endocrinol. Garg A. Acquired and inherited lipodystrophies. N Engl J Med. Genetic syndromes of severe insulin resistance.

Endocr Rev. Karpe F, Pinnick KE. Biology of upper-body and lower-body adipose tissue: link to whole-body phenotypes. Nat Rev Endocrinol. Rydén M, Andersson DP, Bergström IB, Arner P. Adipose tissue and metabolic alterations: regional differences in fat cell size and number matter, but differently: a cross-sectional study.

J Clin Endocrinol Metab. Dahlman I, Rydén M, Brodin D, Grallert H, Strawbridge RJ, Arner P. Numerous genes in loci associated with body fat distribution are linked to adipose function. Lotta LA, Gulati P, Day FR, et al; EPIC-InterAct Consortium; Cambridge FPLD1 Consortium.

Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance. Nat Genet. Scott RA, Fall T, Pasko D, et al; RISC study group; EPIC-InterAct consortium. Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity.

Yaghootkar H, Scott RA, White CC, et al. Yaghootkar H, Lotta LA, Tyrrell J, et al. Genetic evidence for a link between favorable adiposity and lower risk of type 2 diabetes, hypertension, and heart disease.

Sudlow C, Gallacher J, Allen N, et al. UK Biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age.

New genetic loci link adipose and insulin biology to body fat distribution. Day N, Oakes S, Luben R, et al. EPIC-Norfolk: study design and characteristics of the cohort: European Prospective Investigation of Cancer. Br J Cancer. PubMed Google Scholar. Langenberg C, Sharp S, Forouhi NG, et al; InterAct Consortium.

Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study. Genetic studies of body mass index yield new insights for obesity biology.

Scott RA, Lagou V, Welch RP, et al; DIAbetes Genetics Replication and Meta-analysis DIAGRAM Consortium. Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Manning AK, Hivert MF, Scott RA, et al; DIAbetes Genetics Replication And Meta-analysis DIAGRAM Consortium; Multiple Tissue Human Expression Resource MUTHER Consortium.

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.

Willer CJ, Schmidt EM, Sengupta S, et al; Global Lipids Genetics Consortium. Discovery and refinement of loci associated with lipid levels.

Morris AP, Voight BF, Teslovich TM, et al; Wellcome Trust Case Control Consortium; Meta-Analyses of Glucose and Insulin-related Traits Consortium MAGIC Investigators; Genetic Investigation of ANthropometric Traits GIANT Consortium; Asian Genetic Epidemiology Network—Type 2 Diabetes AGEN-T2D Consortium; South Asian Type 2 Diabetes SAT2D Consortium; DIAbetes Genetics Replication And Meta-analysis DIAGRAM Consortium.

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nikpay M, Goel A, Won HH, et al. A comprehensive 1, genomes-based genome-wide association meta-analysis of coronary artery disease.

Eastwood SV, Mathur R, Atkinson M, et al. Algorithms for the capture and adjudication of prevalent and incident diabetes in UK Biobank. PLoS One. Emdin CA, Khera AV, Natarajan P, et al. Genetic association of waist-to-hip ratio with cardiometabolic traits, type 2 diabetes, and coronary heart disease.

Loh PR, Tucker G, Bulik-Sullivan BK, et al. Efficient Bayesian mixed-model analysis increases association power in large cohorts.

Loh PR, Kichaev G, Gazal S, Schoech AP, Price AL. Mixed-model association for Biobank-scale datasets. Willer CJ, Li Y, Abecasis GR. METAL: fast and efficient meta-analysis of genomewide association scans.

Wellcome Trust Case Control Consortium. Genome-wide association study of 14, cases of seven common diseases and 3, shared controls. Aschard H, Vilhjálmsson BJ, Joshi AD, Price AL, Kraft P. Adjusting for heritable covariates can bias effect estimates in genome-wide association studies. Am J Hum Genet.

Stock JHWJ, Yogo M. A survey of weak instruments and weak identification in generalized method of moments. J Bus Econ Stat. Burgess S, Butterworth A, Thompson SG.

Mendelian randomization analysis with multiple genetic variants using summarized data. Genet Epidemiol. Burgess S, Thompson DJ, Rees JMB, Day FR, Perry JR, Ong KK. Dissecting causal pathways using mendelian randomization with summarized genetic data: application to age at menarche and risk of breast cancer.

Causal associations of adiposity and body fat distribution with coronary heart disease, stroke subtypes, and type 2 diabetes mellitus: a mendelian randomization analysis. Danforth E Jr. Failure of adipocyte differentiation causes type II diabetes mellitus?

Virtue S, Vidal-Puig A. Adipose tissue expandability, lipotoxicity and the metabolic syndrome: an allostatic perspective. Biochim Biophys Acta. Haslam DW, James WP. Kan M, Auer PL, Wang GT, et al; NHLBI-Exome Sequencing Project. Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project.

Eur J Hum Genet. Chu AY, Deng X, Fisher VA, et al. Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Low-Fat vs Low-Carbohydrate Diet on Weight Loss in Overweight Adults. This randomized clinical trial compares the effects of a healthy low-fat vs a healthy low-carbohydrate diet on month weight change among adults aged 18 to 50 years with a body mass index of 28 to 40 without diabetes, and investigates modification of the diet effect by genotype pattern or insulin secretion.

Christopher D. Gardner, PhD; John F. Trepanowski, PhD; Liana C. Del Gobbo, PhD; Michelle E. Hauser, MD; Joseph Rigdon, PhD; John P. Ioannidis, MD, DSc; Manisha Desai, PhD; Abby C. King, PhD. JAMA Genomics Website.

See More About Genetics and Genomics Diabetes Diabetes and Endocrinology Cardiology Ischemic Heart Disease Cardiovascular Risk Factors Obesity. Select Your Interests Select Your Interests Customize your JAMA Network experience by selecting one or more topics from the list below.

Save Preferences. Privacy Policy Terms of Use. This Issue. Views 12, Citations View Metrics. X Facebook More LinkedIn. Cite This Citation Lotta LA , Wittemans LBL , Zuber V, et al. Original Investigation. December 25, Luca A.

Lotta, MD, PhD 1 ; Laura B. Wittemans, MSc 1 ; Verena Zuber, PhD 2 ; et al Isobel D. Stewart, PhD 1 ; Stephen J. Day, PhD 1 ; Chen Li, MSc 1 ; Nicholas Bowker, MSc 1 ; Lina Cai, MSc 1 ; Emanuella De Lucia Rolfe, PhD 1 ; Kay-Tee Khaw, MB, ChB, MSc 3 ; John R.

Scott, PhD 1 ; David B. Savage, MD 4 ; Stephen Burgess, PhD 2,3 ; Nicholas J. Wareham, MBBS, PhD 1 ; Claudia Langenberg, MD, PhD 1.

Author Affiliations Article Information 1 MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom. visual abstract icon Visual Abstract. Key Points Question Do genetic variants that are related to body fat distribution via lower levels of gluteofemoral hip fat or via higher levels of abdominal waist fat show associations with diabetes or coronary disease risk?

Study Design. Studies and Participants. Statistical Analysis. Genetic Predisposition to Higher WHR via Lower Gluteofemoral or via Higher Abdominal Fat.

Associations With Cardiometabolic Risk Factors and Disease Outcomes. Back to top Article Information. Access your subscriptions. Obesity Research. July European Journal of Endocrinology. Clinica Chimica Acta; International Journal of Clinical Chemistry. December May April Experimental Biology and Medicine.

Annals of Neurology. BBC News. NBC News. BMC Public Health. ISSN Annales de Réadaptation et de Médecine Physique.

Annals of the New York Academy of Sciences. Bibcode : NYASA The American Journal of Clinical Nutrition. International Journal of Obesity. Journal of the American Society of Nephrology. Prostaglandins, Leukotrienes, and Essential Fatty Acids. Scientific Reports.

Bibcode : NatSR Journal of the International Society of Sports Nutrition. Fertility and Sterility. Iranian Journal of Public Health. Public Health Nutrition.

Canadian Journal of Public Health. Ultra-processed food and drink products in Latin America: Sales, sources, nutrient profiles, and policy implications. ISBN Retrieved 15 March PLOS ONE. Bibcode : PLoSO.. PLOS Medicine. Global Food Security. Mediterranean Journal of Nutrition and Metabolism.

March FASEB Journal. Abnormal obesity and your health. European Journal of Nutrition. A systematic review and meta-analysis". Nutrition Reviews. Abdominal Obesity. Current Opinion in Lipidology. Retrieved on April 9, European Heart Journal. Obesity Before Birth.

Third Report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults ATP III Final Report.

National Institutes of Health. Archived from the original on American Journal of Epidemiology. Preventive Services Task Force Evidence Syntheses HSTAT: Guide to Clinical Preventive Services, 3rd Edition: Recommendations and Systematic Evidence Reviews, Guide to Community Preventive Services.

Current Medical Research and Opinion. International Journal of Hypertension. Expert Review of Cardiovascular Therapy. Metabolic Syndrome and Related Disorders. Obesity Prevention Source. The Journal of the Association of Physicians of India.

Journal of Medical Biochemistry. The American Journal of Physiology. Journal of Sex Research. Visceral fat more of a health concern than subcutaneous fat". Harvard Health Publications. Increasing trends in waist circumference and abdominal obesity among US adults. A case of comparing apples and pears?

Why are women so superior? The Ancel Keys Lecture". Archived from the original on February 9, The Wall Street Journal. Archived from the original on 11 October Retrieved 8 October Archived from the original on 25 January Abbott Laboratories in Germany.

Press release Abbott Laboratories. Archived from the original on 14 October gov in Hong Kong. November 2, Food and Drug Administration of Thailand.

October 20, Archived from the original PDF on May 11, International Journal of Sport Nutrition and Exercise Metabolism. CiteSeerX

New research Abdominal fat distribution little risk of Abdominal fat distribution from fst biopsies. Discrimination at work Avdominal linked to Abdominnal blood pressure. Carbohydrate metabolism in liver fingers and toes: Poor circulation or Raynaud's phenomenon? Body mass indexor Abdominal fat distribution, has long been distribtion standard tool for assessing weight status and health risk. A recent study published in The BMJ analyzed different measures of body shape — more specifically, of central or abdominal fat — to determine which measures were most predictive of premature death. Researchers in this study analyzed the following measurements of central fatness: waist, hip, and thigh circumference; waist-to-hip ratio; waist-to-height ratio; waist-to-thigh ratio; body adiposity index which incorporates hip circumference and height ; and a body shape index calculated from waist circumference, BMI, and height. Abdominal fat distribution diet that included Satiety and satiety index avocado a day reduced visceral belly diatribution in women in a randomized Abdominal fat distribution study of adults with distributlon and obesity. CHAMPAIGN, Abdomibal. One hundred and five Ahdominal with overweight and fa participated in a randomized controlled trial that provided one meal a day for 12 weeks. Women who consumed avocado as part of their daily meal had a reduction in deeper visceral abdominal fat. Led by Naiman Khanan Illinois professor of kinesiology and community healththe researchers published their study, funded by the Hass Avocado Board, in the Journal of Nutrition. Edit embedded media in the Files Tab and re-insert as needed. Individuals with a higher proportion of that deeper visceral fat tend to be at a higher risk of developing diabetes. Abdominal fat distribution

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  1. Entschuldigen Sie, dass ich Sie unterbreche, aber mir ist es etwas mehr die Informationen notwendig.

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